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This imbalanced agonism is a deliberate design feature and contributes to its unique clinical profile

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I think its up for the rest of us to acknowledge that this is a new sign we get in large scale clinical development, but its really linked to the potency of the product. CagriSema is moving into a Phase III trial called REDEFINE 11, where Novo will examine a longer duration, dose escalation and dose re-escalation

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